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Management of Platelet Refractoriness Program Overview

On September 24, 2018, the Blood Systems organization united under one shared name, Vitalant. Programs posted prior to that date may contain legacy branding.

Program Description

The management of the platelet refractory patient presents a challenge for most hospitals and transfusion services. This presentation reviews the pathophysiology and causes of platelet refractoriness. In addition, the presentation reviews current testing methods used for HLA and HPA typing and the detection and identification of alloantibodies that may cause platelet alloimmune refractoriness.

Learning Objectives

Upon completion of the workshop, the participant will be able to:

  • Describe the role of platelets in hemostasis;
  • Describe pathophysiology and causes of platelet refractoriness;
  • Discuss the investigation and diagnosis of refractoriness;
  • Discuss lab tests and management of platelet refractoriness.

Level of Instruction

  • Intermediate

Speaker Credentials

Dolores Figueroa, MT (ASCP) SBB, is an IRL System specialist with Blood Systems, Inc.; she is responsible for the technical direction of the BSI Immunohematology Reference Laboratory reference testing activities. Previously Dolores was the Technical Director for the Blood Systems Laboratories Immunohematology Reference Laboratory (IRL). Dolores joined Blood Systems in July 2000. She holds a certificate in Medical Technology from the University of Puerto Rico, Medical Science Campus. She attended the Atlanta ARC SBB School, and is a certified medical technologist and specialist in blood banking through the American Society of Clinical Pathology (ASCP). The narrator of the presentation is Marie Holub, MA; MT (ASCP) SBB has a Master’s Degree in Education and has worked for Blood Systems for 18 years.

Technical Requirements and Assistance

To view the program material, you need a computer with a supported web browser and a dial-up or better internet connection. The supported operating systems and web browsers are:

Operating Systems

  • Windows 2000, XP, Vista, Windows 7
  • MacOS X 10.4 or later
  • Linux 2.6 with KDE or Gnome

Web Browsers

  • Internet Explorer 6 or later
  • Firefox 2 or later
  • Safari 3 or later
  • Opera 9 or later

Technical Support

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